Demographic, clinical, and paraclinical characteristics including disease activity (DAS28), erosive status (Sharp-van der Heijde score), and physical disability (HAQ score) of 158 patients with early untreated RA by anti-CCP status. Data are median (range).
| All Patients, n = 158 | Anti-CCP-positive, n = 93 | Anti-CCP-negative, n = 65 | p† | |
|---|---|---|---|---|
| Age, yrs | 53 (20–75) | 53 (22–75) | 53 (20–73) | 0.92* |
| Women (% of patients) | 105 (66.4) | 59 (63.4) | 46 (70.8) | 0.34** |
| Duration since first symptom, wks | 14 (6.3–27) | 15 (6.3–26) | 14 (6.3–27) | 0.84* |
| Disease activity | 5.5 (2.2–8.4) | 5.6 (2.2–8.4) | 5.5 (2.4–7.9) | 0.86* |
| Erosive status | 3 (0–37) | 4 (0–37) | 2 (0–26) | 0.11* |
| Physical disability | 1.0 (0–2.9) | 1.0 (0–2.9) | 0.75 (0–2.4) | 0.10* |
| MBL2 genotypes | 0.17*** | |||
| Homozygous-defective, 0/0 (%) | 8 (5.1) | 5 (5.4) | 3 (4.6) | |
| Intermediate group (%) | 101 (63.9) | 54 (58.0) | 47 (72.3) | |
| High producers, YA/YA (%) | 49 (31.0) | 34 (36.6) | 15 (23.1) |