Hazard ratio of organ damage (n = 141) by cumulative average dose of prednisone.
| Cumulative Average Prednisone | Unadjusted Model | Conventionally-Adjusted Model* | Weighted Model* | |||||
|---|---|---|---|---|---|---|---|---|
| Dose (mg/mo) | % of Patient-mos | No. of Events | HR | 95% CI | HR | 95% CI | HR | 95% CI |
| 0 | 35.9 | 34 | Ref | Ref | Ref | |||
| > 0–180 | 37.0 | 49 | 1.58 | 1.00, 2.50 | 2.01 | 1.11, 3.63 | 1.16 | 0.54, 2.50 |
| > 180–360 | 14.9 | 29 | 2.10 | 1.24, 3.55 | 2.46 | 1.17, 5.16 | 1.50 | 0.58, 3.88 |
| > 360–540 | 6.7 | 18 | 3.04 | 1.67, 5.53 | 3.54 | 1.55, 8.12 | 1.64 | 0.58, 4.69 |
| > 540 | 5.5 | 21 | 4.19 | 2.35, 7.47 | 4.10 | 1.74, 9.65 | 2.51 | 0.87, 7.27 |
↵* Adjusted for age, sex, race/ethnicity, baseline prednisone dose, baseline SLE activity, baseline organ damage, and time-varying covariates. HR: hazard ratio.