* Concomitant malignant disease and chemotherapy1,17,38,66,79 * Glucocorticoid therapy1,17,35,66,80 * Diabetes1,38,81 * Advanced age: in review of cases of ONJ in patients with multiple myeloma, there was a 9% increase in the risk of developing ONJ with each decade of life82 * Smoking and alcohol need to be evaluated further |