OMERACT 7 Voting† | Patient Delphi ‡ | |||
---|---|---|---|---|
Domain | % | Domain/item | Mean | % |
Pain | 100 | Pain or physical discomfort | 6.9 | 95 |
Patient global | 94 | Joints aching or pain | 5.7 | 90 |
Fatigue | 85 | Lack of energy or fatigue | 5.5 | 96 |
HRQOL | 76 | Impact on sleep [e.g., difficulty falling asleep, staying asleep, or getting up in the morning] | 5.3 | 92 |
Multidimensional function | 75 | Problems with attention or concentration [e.g., difficulty concentrating on things, difficulty thinking, “fibro-fog’] | 4.7 | 91 |
Sleep | 70 | Stiffness | 4.2 | 91 |
Depression | 65 | Disorganized thinking [e.g., difficulty expressing yourself, difficulty answering questions quickly, or difficulty making plans] | 3.6 | 85 |
Treatment side effects | 58 | Difficulty moving, walking, or exercising | 3.5 | 86 |
Physical function | 42 | Having to push yourself to do things | 3.1 | 83 |
Clinical global | 23 | Impact on ability to make plans, accomplish goals, or complete tasks | 3.0 | 79 |
Tender point intensity | 21 | Feeling tender where touched | 3.0 | 77 |
Dyscognition | 21 | Depression (e.g., disappointed, sad, resigned, or unmotivated) | 3.0 | 74 |
Anxiety | 21 | Impacted/limited in doing normal daily life and household activities | 2.8 | 82 |
Memory problems | 2.6 | 81 |
↵† FM domains ranked as most important in clinician-investigator Delphi exercise performed prior to OMERACT 7. Percent column shows percentage of OMERACT 7 attendees who agreed these domains were essential to assess in FM clinical trials.
↵‡ Mean scores [points assigned out of 100 possible] for the top 14 domains identified by patients as important in FM. Percentage column reflects percentage of patients who felt domains should be assessed. HRQOL: health-related quality of life.