Table 6.

Risk of cardiovascular outcomes in subjects with autoantibody testing vs matched control subjects without autoantibody testing.

AutoantibodyOutcomeEventsHazard Ratio (95% CI)*
RFMI, HF, or PVD**2301.04 (0.78, 1.37)
Death2640.95 (0.73, 1.24)
ANAMI, HF, or PVD**2151.20 (0.93, 1.56)
Death2180.93 (0.73, 1.19)
  • * Adjusted for age, sex, calendar year, comorbidity, and presence of rheumatic disease.

  • ** Defined as first occurrence of any of the 3 events. RF: rheumatoid factor; ANA: antinuclear antibody; MI: myocardial infarction; HF: heart failure; PVD: peripheral vascular disease; HR: hazard ratio; comorbidity: chronic disease comorbidities9.