Table 2.

Risk of autoantibody positivity on cardiovascular outcomes and death.

Autoantibody	Outcome	Events	Hazard Ratio (95% CI)
Autoantibody	Outcome	Events	Unadjusted for Presence of Rheumatic Disease^*	Adjusted for Presence of Rheumatic Disease^*
RF	MI	365	1.36 (1.03, 1.79)	1.22 (0.91, 1.64)
	HF	499	1.47 (1.17, 1.84)	1.36 (1.07, 1.73)
	PVD	507	1.13 (0.88, 1.46)	1.08 (0.82, 1.43)
	MI, HF, or PVD^**	871	1.32 (1.10, 1.59)	1.24 (1.01, 1.51)
	Death	998	1.55 (1.33, 1.80)	1.43 (1.21, 1.68)
ANA	MI	371	1.32 (1.06, 1.65)	1.29 (1.03, 1.61)
	HF	502	1.13 (0.93, 1.38)	1.11 (0.92, 1.35)
	PVD	522	1.37 (1.13, 1.66)	1.35 (1.12, 1.64)
	MI, HF, or PVD^**	890	1.28 (1.10, 1.48)	1.26 (1.09, 1.46)
	Death	1142	1.19 (1.05, 1.35)	1.18 (1.04, 1.34)

↵* Adjusted for age, sex, calendar year, comorbidity.
↵** Defined as first occurrence of any of the 3 events. RF: rheumatoid factor; ANA: antinuclear antibody; MI: myocardial infarction; HF: heart failure; PVD: peripheral vascular disease; comorbidity: Charlson⁹ category comorbidities.