Variable | Polymyalgia Rheumatica without GCA, n = 13 | Arteriosclerosis, GCA, n = 20 | GCA, n = 27 | p |
---|---|---|---|---|
Age, yrs, mean ± SD | 69.8 ± 10.0 | 72.6 ± 10.5 | 73.4 ± 8.0 | NS |
Sex, n (%) | ||||
Female | 5 (38.5) | 7 (35.0) | 9 (33.3) | NS |
Male | 8 (61.5) | 13 (65.0) | 18 (66.6) | |
Erythrocyte sedimentation rate, mm/h, mean ± SD | 91.9 ± 9.3 | 51.6 ± 31.0 | 88.1 ± 11.9 | *** |
Leukocytes, g/l, mean ± SD | 11.1 ± 3.0 | 9.5 ± 3.1 | 9.4 ± 2.3 | NS |
C-reactive protein, mg/dl, mean ± SD | 10.3 ± 10.9 | 3.5 ± 4.8 | 8.6 ± 5.1 | NS |
Hemoglobin, g/l, mean ± SD | 116 ± 17 | 121 ± 18 | 111 ± 19 | NS |
Glucose, mg/dl, mean ± SD | 162.0 ± 99.3 | 134.9 ± 79.7 | 116.4 ± 52.3 | NS |
Diabetes, n (%) | 5 (40.7) | 6 (35.3) | 5 (20.8) | NS |
ND | 1 | 3 | 3 | |
Creatinine, mg/dl, mean ± SD | 1.96 ± 2.9 | 0.98 ± 0.37 | 0.84 ± 0.29 | NS |
Anti-DNA | 1 positive case in the arteriosclerosis group | |||
ANA | All negative | |||
RF, n (%) | 0 (0) | 1 (20.0) | 8 (72.7) | Too few cases for analysis |
ND | 9 | 15 | 16 | |
c-ANCA (myeloperoxidase) | All negative | |||
p-ANCA (proteinase 3) | 0 | 0 | 2 (13.3) | NS |
ND | 6 | 13 | 12 | |
Hypertonia, n (%) | 3 (25.0) | 13 (72.2) | 12 (50.0) | NS |
ND | 1 | 2 | 3 | |
Aching in shoulder girdle, n (%) | 9 (75.0) | 6 (35.3) | 6 (25) | NS |
ND | 1 | 3 | 3 | |
Aching of hip girdle, n (%) | 5 (41.7) | 0 (0) | 10 (41.7) | NS |
ND | 1 | 4 | 3 | |
Impaired vision, n (%) | 1 (8.3) | 3 (18.8) | 7 (29.2) | NS |
ND | 1 | 4 | 3 | |
Fever, n (%) | 4 (33.3) | 3 (20) | 7 (29.2) | NS |
ND | 1 | 5 | 3 | |
Night sweats, n (%) | 5 (41.7) | 4 (26.7) | 13 (56.5) | NS |
ND | 1 | 5 | 4 | |
Weight loss, n (%) | 5 (41.7) | 8 (50) | 17 (73.9) | NS |
ND | 1 | 4 | 4 | |
Jaw claudication, n (%) | 0 (0) | 0 (0) | 11 (91.7) | *** |
ND | 2 | 4 | 15 | |
Headache, n (%) | 5 (44.8) | 10 (62.5) | 17 (77.3) | NS |
ND | 1 | 4 | 7 |
ND: not determined; NS: not significant;
↵*** highly significant; ANA: antinuclear antibodies; RF: rheumatoid factor; c-ANCA: cytoplasmic antineutrophil cytoplasmic antibodies; p-ANCA: perinuclear ANCA.