OR (95% CI) | ||||
---|---|---|---|---|
Crude | p | Adjusted* | p | |
TT genotype + nonsmoking | 1.0 (reference) | 1.0 (reference) | ||
TT genotype + smoking | 1.92 (1.16–3.17) | 0.011 | 2.39 (1.36–4.23) | 0.003 |
G allele carrier + nonsmoking | 1.38 (0.85–2.23) | 0.186 | 1.33 (0.77–2.32) | 0.307 |
G allele carrier + smoking | 3.42 (1.73–6.74) | < 0.0001 | 5.42 (2.48–11.84) | < 0.0001 |
Multiplicative interaction measure | 1.29 (0.53–3.14) | 0.576 | 1.70 (0.62–4.61) | 0.300 |
Additive interaction measure | ||||
Relative excess due to interaction | 1.12 (−1.205 to 3.44) | 0.345 | 2.65 (−1.35 to 6.65) | 0.194 |
Attributable proportion due to interaction | 0.33 (−0.18 to 0.84) | 0.205 | 0.49 (0.07–0.92) | 0.023 |
Synergy index | 1.87 (0.57–6.21) | 0.304 | 2.54 (0.80–8.09) | 0.114 |
↵* Adjusted for age, region, and alcohol intake.