Table 2.

Association between STAT4 and TNFRSF1B genotypes and risk of SLE.

	Cases/Controls		OR (95% CI)
	Number	Minor Allele Frequency	Crude	p	Adjusted^*	p
STAT4 rs7574865
GG	61/217		1.0		1.0
TG	68/172		1.41 (0.94–2.10)	0.094	1.31 (0.83–2.08)	0.242
TT (ancestral)	23/38		2.15 (1.19–3.89)	0.011	2.21 (1.10–4.68)	0.027
TT (ancestral)			p for trend = 0.008		p for trend = 0.029
GT + TT	91/210	0.375/0.290	1.54 (1.06–2.24)	0.024	1.46 (0.95–2.25)	0.087
TNFRSF1B rs1061622^**
TT (ancestral)	97/310		1.0		1.0
TG	53/111		1.53 (1.02–2.28)	0.038	1.59 (1.00–2.52)	0.049
GG	1/3		1.07 (0.11–10.36)	0.957	0.86 (0.07–10.14)	0.904
GG			p for trend = 0.050		p for trend = 0.075
TG + GG	54/114	0.1827/0.138	1.51 (1.02–2.25)	0.040	1.56 (0.99–2.47)	0.056

↵* Adjusted for age, region, smoking status, and alcohol intake.
↵** Four women (1 case and 3 controls) were missing genotype data.