Table 2.

RA characteristics and their associations with the risk of heart failure (HF) in 795 incident RA patients. Values are given as number (%) if not indicated otherwise.

CharacteristicsValueHazard Ratio ** (95% CI), Adjusted for Age, Sex, and Calendar Year of RA Incidence
RF-positive527 (66)1.6 (1.0, 2.5)
ESR at RA incidence, mm/h, mean ± SD24.2 ± 19.91.6 (1.2, 2.0)
≥ 3 ESR ≥ 60 mm/h99 (12)2.1 (1.2, 3.5)
Large-joint swelling624 (78)1.1 (0.7, 1.8)
Joint erosions/destructive changes424 (53)1.1 (0.8, 1.7)
Joint surgery
  Arthroplasty134 (17)1.5 (0.9, 2.5)
  Synovectomy86 (11)1.1 (0.6, 2.2)
Rheumatoid nodules266 (33)1.1 (0.7, 1.7)
Severe ExRA*87 (11)3.1 (1.9, 5.1)
History of rheumatic fever22 (3)1.0 (0.4, 2.7)
  • * Malmö criteria32.

  • ** Significant (p < 0.05) hazard ratios are shown in bold type.

  • Per 30 mm/h increase. RA: rheumatoid arthritis; RF: rheumatoid factor; ESR: erythrocyte sedimentation rate; ExRA: extraarticular manifestations of RA.