Disease* (ICD-9 code): 1136 Diagnoses in 824 Individuals | Administrative Diagnosis (All Positive) | Diagnosis on Chart Review | True-Positive | False-Positive | True-Negative | False-Negative | Sensitivity, % (95% CI) | Specificity, % (95% CI) |
---|---|---|---|---|---|---|---|---|
SLE (710.0) | 386 | 225 | 221 | 165 | 434 | 4 | 98.2 (95.5, 99.3) | 72.5 (68.7, 75.9) |
SSc (710.1) | 104 | 82 | 66 | 38 | 704 | 16 | 80.5 (70.6, 87.6) | 94.9 (93.0, 96.2) |
Myositis (710.3–4) | 66 | 43 | 38 | 28 | 753 | 5 | 88.4 (75.5, 94.9) | 96.4 (94.9, 97.5) |
Sjögren’s syndrome (710.2) | 115 | 88 | 84 | 31 | 705 | 4 | 95.5 (88.8, 98.2) | 95.8 (94.1, 97.0) |
Vasculitis (446) | 120 | 92 | 86 | 34 | 698 | 6 | 93.5 (86.5, 97.0) | 95.4 (93.6, 96.7) |
PMR (725) | 235 | 186 | 185 | 50 | 588 | 1 | 99.5 (97.0, 99.9) | 92.2 (89.8, 94.0) |
Other† | 110 | 65 | — | — | — | — | — | — |
↵* Cases identified on the basis of hospitalization (≥ 1 discharge diagnosis) or physician billing (> 2 diagnoses by any physician ≥ 8 weeks apart but within 2 years, or ≥ 1 diagnosis by a rheumatologist).
↵† Includes 710.8 — other specified diffuse diseases of connective tissue, and 710.9 — unspecified diffuse connective tissue disease. ICD-9: International Classification of Diseases, 9th ed.; SLE: systemic lupus erythematosus; SSc: systemic sclerosis; myositis: includes dermatomyositis and polymyositis; PMR: polymyalgia rheumatica.