Lymphotoxin-α (LTA) 252 genotype and allele frequencies. Values calculated with the G/G genotype as reference.
| Patients with RA, n = 388 | Control Subjects, n = 269 | p | OR (95% CI) | |
|---|---|---|---|---|
| LTA 252 genotypes | ||||
| A/A | 197 (50.8%) | 117 (43.5%) | 0.025 | 1.772 (1.076–2.921) |
| A/G | 153 (39.4%) | 112 (41.6%) | 0.160 | 1.438 (0.867–2.386) |
| G/G | 38 (9.8%) | 40 (14.9%) | ||
| Allele frequency | ||||
| A allele | 547 (70.5%) | 346 (64.3%) | 0.018 | 1.325 (1.049–1.675) |
| G allele | 229 (29.5%) | 192 (35.7%) | 0.018 | 0.754 (0.597–0.954) |