Table 2.

Descriptive data on the number of corner inflammatory lesions (CIL) recorded in the anterior cervical and lumbar spine at baseline and at followup MRI. Results are given for concordant and individual reads.

CIL DataConcordant ReadsFirst ReaderSecond Reader
TNF-α Inhibitor Therapy n = 23Standard Therapy n = 27TNF-α Inhibitor Therapy n = 23Standard Therapy n = 27TNF-α Inhibitor Therapy n = 23Standard Therapy n = 27
Baseline MRI (total no. spinal sites)474599552648552648
Total number (%) of CIL32 (6.8)23 (3.8)86 (15.6)62 (9.6)56 (10.1)33 (5.1)
  No. CIL per patient
    Mean (SD)1.4 (1.53)0.85 (1.81)3.74 (2.63)2.30 (2.30)2.43 (1.97)1.22 (1.91)
    Median (IQR)1 (0–2)0 (0–1)3 (2–5)2 (1–3)2 (1–3.5)1 (0–1.5)
    Range0–60–90–100–100–70–9
Followup MRI
Total number of CIL111653492522
  CIL per patient
    Mean (SD)0.48 (1.20)0.59 (1.45)2.30 (2.48)1.81 (2.06)1.09 (2.17)0.81 (1.66)
    Median (IQR)0 (0–0)0 (0–1)1 (0–4)1 (0.5–2)0 (0–2)0 (0–1)
    Range0–50–70–100–80–100–7
No. completely resolved CIL14742224420
No. new CIL1399139
  • IQR: interquartile range; MRI: magnetic resonance imaging; TNF-α: tumor necrosis factor-α. First reader: PC; second reader: SJP.