Characteristics | RA Total, n = 388 | A/A, n = 197 | A/G, n = 153 | G/G, n = 38 | p |
---|---|---|---|---|---|
Women | 344 (88.7) | 173 (87.8) | 137 (89.5) | 34 (89.5) | 0.87 |
Age, yrs | 58 (48–67) | 59 (49.5–67) | 59 (50.5–67) | 45 (35–59) | 0.001 |
Body mass index, kg/m2 | 26.7 (23.1–29.7) | 27.2 (23.5–29.2) | 26.6 (23.5–30.6) | 24.7 (21.4–28.1) | 0.19 |
Waist, cm | 87.2 (11.3) | 87.5 (10) | 87.6 (12) | 85.9 (15) | 0.57 |
Current smoker | 52 (13.4) | 12 (6.1) | 34 (22.2) | 6 (15.8) | 0.02 |
Age at RA onset | 44 (32–55) | 45 (34.5–55.5) | 46 (33–56) | 34 (22–43) | < 0.0001 |
Disease duration, yrs | 10 (4.4–18) | 10 (4.7–19.3) | 10 (4.2–18.9) | 10 (4.1–18.2) | 0.88 |
Rheumatoid factor-positive | 284 (73.2) | 139 (70.6) | 116 (75.8) | 29 (76.3) | 0.58 |
DAS28 | 4.1 (3.0–5.3) | 3.9 (2.9–5.2) | 3.9 (3.0–5.5) | 4.5 (3.5–5.1) | 0.65 |
HAQ | 1.125 (0.5–1.87) | 1 (0.5–1.75) | 1.25 (0.62–1.87) | 1.25 (0.25–1.84) | 0.58 |
Erosions, n = 284 | 235 (82.7) | 133 (87.5) | 85 (80.2) | 17 (65.4) | 0.015 |
Extraarticular features | 96 (24.7) | 52 (26.4) | 36 (23.5) | 8 (21.1) | 0.71 |
Joint surgery | 52 (13.4) | 22 (11.2) | 28 (18.3) | 2 (5.3) | 0.34 |
Corticosteroids | 262 (67.5) | 136 (69) | 105 (68.6) | 21 (55.3) | 0.46 |
Methotrexate | 292 (75.3) | 146 (74.1) | 121 (79) | 25 (65.8) | 0.43 |
Biologics | 74 (19) | 37 (18.8) | 32 (20.9) | 5 (12.8) | 0.51 |
DAS: Disease Activity Score; HAQ: Health Assessment Questionnaire.