RT Journal Article
SR Electronic
T1 Concomitant therapy: an outcome variable for musculoskeletal disorders? Part 2: total joint replacement in osteoarthritis trials.
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 2449
OP 2451
VO 32
IS 12
A1 Jean-Francis Maillefert
A1 Gillian A Hawker
A1 Laure Gossec
A1 Nizar N Mahomed
A1 Stefan Lohmander
A1 Paul A Dieppe
A1 Gustavo Zanoli
A1 Marc C Hochberg
A1 Maxime Dougados
A1 OMERACT 7 Special Interest Group
YR 2005
UL http://www.jrheum.org/content/32/12/2449.abstract
AB Interest has grown in using the requirement of total joint replacement (TJR) as a "hard" outcome measure. Limitations exist, however, in the use of such an outcome, in particular the variability in the decision to perform surgery, length of surgical waiting lists, and sensitivity to change. This special interest group is exploring ways of retaining the clinical relevance of TJR but overcoming the problems--2 alternative outcomes are being considered: "time to physician's decision to recommend surgery" and "time to fulfilling criteria for total joint replacement."