TY - JOUR T1 - Concomitant therapy: an outcome variable for musculoskeletal disorders? Part 2: total joint replacement in osteoarthritis trials. JF - The Journal of Rheumatology JO - J Rheumatol SP - 2449 LP - 2451 VL - 32 IS - 12 AU - Jean-Francis Maillefert AU - Gillian A Hawker AU - Laure Gossec AU - Nizar N Mahomed AU - Stefan Lohmander AU - Paul A Dieppe AU - Gustavo Zanoli AU - Marc C Hochberg AU - Maxime Dougados AU - OMERACT 7 Special Interest Group Y1 - 2005/12/01 UR - http://www.jrheum.org/content/32/12/2449.abstract N2 - Interest has grown in using the requirement of total joint replacement (TJR) as a "hard" outcome measure. Limitations exist, however, in the use of such an outcome, in particular the variability in the decision to perform surgery, length of surgical waiting lists, and sensitivity to change. This special interest group is exploring ways of retaining the clinical relevance of TJR but overcoming the problems--2 alternative outcomes are being considered: "time to physician's decision to recommend surgery" and "time to fulfilling criteria for total joint replacement." ER -