PT - JOURNAL ARTICLE AU - Henda Bouali AU - Eric J Deppert AU - Lawrence J Leventhal AU - Brian Reeves AU - Thomas Pope TI - Pigmented villonodular synovitis: a disease in evolution. DP - 2004 Aug 01 TA - The Journal of Rheumatology PG - 1659--1662 VI - 31 IP - 8 4099 - http://www.jrheum.org/content/31/8/1659.short 4100 - http://www.jrheum.org/content/31/8/1659.full SO - J Rheumatol2004 Aug 01; 31 AB - Pigmented villonodular synovitis (PVNS) is a rare, benign, proliferative disease of the synovial membrane of joints, tendon sheaths, and bursas. Joint aspiration typically yields hemorrhagic or xanthochromic/serosanguinous (brown, murky) fluid. We describe a case of PVNS that presented as an acute, painless, nontraumatic right knee effusion with clear synovial fluid on arthrocentesis. Initial magnetic resonance imaging of the knee revealed no evidence for hemosiderin. A diagnostic arthroscopy and surgical arthrotomy revealed a unique case of PVNS evolving from local to diffuse involvement of the synovium.