RT Journal Article SR Electronic T1 Vasculitis associated with the use of leflunomide. JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 2076 OP 2078 VO 31 IS 10 A1 Jeannie Macdonald A1 Toni Zhong A1 Adriana Lazarescu A1 Bing Siang Gan A1 Manfred Harth YR 2004 UL http://www.jrheum.org/content/31/10/2076.abstract AB Vasculitis as a complication of leflunomide therapy in the treatment of rheumatoid arthritis has been reported. We describe a case of acute necrotizing vasculitis following leflunomide therapy. Characteristics of this case and 4 cases in the literature suggest that vasculitis may be a rare but serious adverse effect of leflunomide therapy.