RT Journal Article SR Electronic T1 Macrophage activation syndrome following initiation of etanercept in a child with systemic onset juvenile rheumatoid arthritis. JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 401 OP 403 VO 30 IS 2 A1 Athimalaipet V Ramanan A1 Rayfel Schneider YR 2003 UL http://www.jrheum.org/content/30/2/401.abstract AB Systemic onset juvenile rheumatoid arthritis (JRA) accounts for 10-15% of all JRA. Macrophage activation syndrome (MAS), which can also be considered as secondary hemophagocytic lymphohistiocytosis, is a potentially life-threatening complication of systemic onset JRA. We describe a child with systemic onset JRA who developed MAS after initiation of etanercept therapy.