TY - JOUR T1 - Severe Raynaud's phenomenon with yohimbine therapy for erectile dysfunction. JF - The Journal of Rheumatology JO - J Rheumatol SP - 2503 LP - 2505 VL - 30 IS - 11 AU - Sindhu Johnson AU - John Iazzetta AU - Catharine Dewar Y1 - 2003/11/01 UR - http://www.jrheum.org/content/30/11/2503.abstract N2 - Yohimbine is a selective alpha-2 adrenergic antagonist that has been used in the pharmacologic management of erectile dysfunction (ED). We describe a patient with CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia) who paradoxically experienced worsening of Raynaud's phenomenon when using yohimbine for ED. ER -