PT  - JOURNAL ARTICLE
AU  - P A Simkin
TI  - Acetabular osteitis in ankylosing spondylitis: does fibrillin figure in its pathogenesis?
DP  - 2001 Dec 01
TA  - The Journal of Rheumatology
PG  - 2663--2666
VI  - 28
IP  - 12
4099  - http://www.jrheum.org/content/28/12/2663.short
4100  - http://www.jrheum.org/content/28/12/2663.full
SO  - J Rheumatol2001 Dec 01; 28
AB  - In the hip and sacroiliac joints, ankylosing spondylitis attacks the acetabulum over the femoral head and the ilium in preference to the sacrum. Both sites involve inflammation in bone subjacent to fibrocartilage with relative sparing of opposing, hyaline cartilage-surfaced mates. This disease appears to target connective tissues rich in fibrillin-1. A cell-mediated autoimmune response may be involved.