RT Journal Article
SR Electronic
T1 Antibodies to beta 2-glycoprotein I and cardiolipin with symptoms suggestive of systemic lupus erythematosus in parvovirus B19 infection.
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 2335
OP 2336
VO 28
IS 10
A1 M Kalt
A1 E Gertner
YR 2001
UL http://www.jrheum.org/content/28/10/2335.abstract
AB Parvovirus B 19 infection may mimic systemic lupus erythematosus (SLE) in its clinical presentation. Serological abnormalities during acute infection have been reported, including positive antinuclear antibodies and anti-doublestranded DNA antibodies. We describe a patient who, in addition to the clinical and laboratory findings suggestive of SLE, was found to have antibodies to cardiolipin and beta2 glycoprotein I. The symptoms resolved and the antibodies disappeared over a 9 month period. This report highlights the striking similarity between SLE and parvovirus B19 infection and the potential difficulty in distinguishing between the diseases.