RT Journal Article
SR Electronic
T1 Number of births, interpregnancy interval, and subsequent pregnancy rate after a diagnosis of inflammatory rheumatic disease in Norwegian women.
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 2310
OP 2314
VO 28
IS 10
A1 J F Skomsvoll
A1 M Ostensen
A1 V Baste
A1 L M Irgens
YR 2001
UL http://www.jrheum.org/content/28/10/2310.abstract
AB OBJECTIVE: To study female reproduction, i.e., number of births, subsequent pregnancy rate, and interpregnancy interval after diagnosis of inflammatory rheumatic disease. METHODS: In a national population based cohort study, reproduction in mothers with rheumatic disease, registered with the Medical Birth Registry of Norway 1967-1995, were compared to mothers without such diagnoses. RESULTS: After diagnosis, women with rheumatic disease had a statistically significant lower mean number of births, a shorter time span of reproduction, longer interpregnancy intervals, and a reduced subsequent pregnancy rate. CONCLUSION: Altered reproduction observed in women with a rheumatic disease might reflect various mechanisms not accounted for in this study, but possibly related to the disease process, functional impairment, or medical treatment.