RT Journal Article
SR Electronic
T1 Differential Features Between Primary Ankylosing Spondylitis and Spondylitis Associated with Psoriasis and Inflammatory Bowel Disease
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1656
OP 1660
DO 10.3899/jrheum.101049
VO 38
IS 8
A1 RODOLFO PÉREZ ALAMINO
A1 JOSÉ A. MALDONADO COCCO
A1 GUSTAVO CITERA
A1 PABLO ARTURI
A1 JANITZIA VAZQUEZ-MELLADO
A1 PERCIVAL D. SAMPAIO-BARROS
A1 DIANA FLORES
A1 RUBÉN BURGOS-VARGAS
A1 HELENA SANTOS
A1 JOSÉ E. CHAVEZ-CORRALES
A1 DANIEL PALLEIRO
A1 MIGUEL A. GUTIERREZ
A1 ELSA VIEIRA-SOUSA
A1 FERNANDO M. PIMENTEL-SANTOS
A1 SERGIO PAIRA
A1 ALBERTO BERMAN
A1 MARIO MORENO-ALVAREZ
A1 EDUARDO COLLANTES-ESTEVEZ
YR 2011
UL http://www.jrheum.org/content/38/8/1656.abstract
AB Objective. To describe differential characteristics of axial involvement in ankylosing spondylitis (AS) as compared with that seen in psoriatic arthritis (PsA) and inflammatory bowel disease (IBD) in a cohort of Ibero-American patients. Methods. This study included 2044 consecutive patients with spondyloarthritis (SpA; ESSG criteria). Demographic, clinical, disease activity, functional ability, quality of life, work status, radiologic, and therapeutic data were evaluated and collected by RESPONDIA members from different Ibero-American countries between June and December 2006. Patients selected for analysis met modified New York criteria (mNY) for AS. Results. A total of 1264 patients met the New York criteria for AS: 1072 had primary AS, 147 had psoriatic, and 45 had IBD-associated spondylitis. Median disease duration was comparable among the 3 patient groups. Patients with primary AS were significantly younger (p = 0.01) and presented a higher frequency of males (p = 0.01) than the other 2 groups. Axial manifestations such as inflammatory back pain and sacroiliac pain were significantly more frequent in patients with primary AS (p = 0.05) versus other groups, whereas frequency of dactylitis, enthesitis, and peripheral arthritis was more common in patients with psoriatic spondylitis (p = 0.05). Spinal mobility was significantly more limited in patients with primary AS versus the other 2 groups (p = 0.0001). Radiologic changes according to BASRI total score were equally significant in primary AS. Disease activity (BASDAI), functional ability (BASFI), and quality of life (ASQoL) scores were comparable in the 3 groups. Conclusion. Patients with primary AS had more severe axial involvement than those with spondylitis associated with psoriasis or IBD. Functional capacity, disease activity, and quality of life were comparable among the groups studied.