RT Journal Article SR Electronic T1 SARS-CoV-2: Viral Mechanisms and Possible Therapeutic Targets – What to learn from Rheumatologists? JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP jrheum.200657 DO 10.3899/jrheum.200657 A1 Carlos Antonio Mouraa A1 Ana Luísa Cerqueira de Sant’Ana Costa YR 2020 UL http://www.jrheum.org/content/early/2020/05/20/jrheum.200657.abstract AB It was with great interest that we read the letter from Randy Cron and collaborators (1) linking the cytokine storm syndrome (CSS) seen in macrophage activation syndrome, common in the rheumatological setting, with the CSS postulated to be a background in the novel coronavirus (SARS-CoV-2) infection. Amid the high contagiousness of the virus, science was also infected by an infodemia, compelled to enter a race to find effective therapies studying mechanisms molecular aspects of SARS-CoV-2 concomitant to urgent bedside manage of patients.