PT - JOURNAL ARTICLE AU - Carlos Antonio Mouraa AU - Ana Luísa Cerqueira de Sant’Ana Costa TI - SARS-CoV-2: Viral Mechanisms and Possible Therapeutic Targets – What to learn from Rheumatologists? AID - 10.3899/jrheum.200657 DP - 2020 May 25 TA - The Journal of Rheumatology PG - jrheum.200657 4099 - http://www.jrheum.org/content/early/2020/05/20/jrheum.200657.short 4100 - http://www.jrheum.org/content/early/2020/05/20/jrheum.200657.full AB - It was with great interest that we read the letter from Randy Cron and collaborators (1) linking the cytokine storm syndrome (CSS) seen in macrophage activation syndrome, common in the rheumatological setting, with the CSS postulated to be a background in the novel coronavirus (SARS-CoV-2) infection. Amid the high contagiousness of the virus, science was also infected by an infodemia, compelled to enter a race to find effective therapies studying mechanisms molecular aspects of SARS-CoV-2 concomitant to urgent bedside manage of patients.