RT Journal Article
SR Electronic
T1 Large Vessel Vasculitis Affecting the Aorta and Its Branches in Relapsing Polychondritis: Case Series and Systematic Review of the Literature
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP jrheum.190862
DO 10.3899/jrheum.190862
A1 Alessandro Tomelleri
A1 Corrado Campochiaro
A1 Silvia Sartorelli
A1 Maurizio Papa
A1 Giacomo De Luca
A1 Giulio Cavalli
A1 Elena Baldissera
A1 Lorenzo Dagna
YR 2019
UL http://www.jrheum.org/content/early/2019/12/09/jrheum.190862.abstract
AB Objective To describe the features of large vessel vasculitis (LVV) affecting the aorta and its branches in relapsing polychondritis (RP) patients. Methods Retrospective data and systematic literature review. Results 21 patients were identified. LVV diagnosis was subsequent to RP and associated with extra-chondral involvement in the majority of patients. Supra-aortic vessels were more frequently involved (82%). 14 (67%) patients were treated with a csDMARD and 7 (33%) with a bDMARD. Vascular interventional procedures were performed in 10 (48%) patients. Prematurely death due to cardiovascular complications was reported in 3 (14%) cases. Conclusion Extra-aortic LVV is a serious and overlooked RP manifestation. All RP patients should be investigated for LVV.