TY - JOUR T1 - Drs. Deane and Demoruelle reply JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.191060 SP - jrheum.191060 AU - Kevin D. Deane AU - M. Kristen Demoruelle Y1 - 2019/12/01 UR - http://www.jrheum.org/content/early/2019/11/25/jrheum.191060.abstract N2 - In the letter by Alpizar-Rodriguez and Finckh1, they describe their prior work in which they found, similar to our current report, an association between older age and anticitrullinated protein antibody (ACPA) positivity in first-degree relatives (FDR) of patients with rheumatoid arthritis (RA)2,3. In contrast to our findings, their data suggest that the strongest association between ACPA positivity and age is in women aged 45–55 years, and they did not find an association between ACPA positivity and age in men. ER -