PT  - JOURNAL ARTICLE
AU  - Kevin D.  Deane
AU  - M. Kristen  Demoruelle
TI  - Drs. Deane and Demoruelle reply
AID  - 10.3899/jrheum.191060
DP  - 2019 Dec 01
TA  - The Journal of Rheumatology
PG  - jrheum.191060
4099  - http://www.jrheum.org/content/early/2019/11/25/jrheum.191060.short
4100  - http://www.jrheum.org/content/early/2019/11/25/jrheum.191060.full
AB  - In the letter by Alpizar-Rodriguez and Finckh1, they describe their prior work in which they found, similar to our current report, an association between older age and anticitrullinated protein antibody (ACPA) positivity in first-degree relatives (FDR) of patients with rheumatoid arthritis (RA)2,3. In contrast to our findings, their data suggest that the strongest association between ACPA positivity and age is in women aged 45–55 years, and they did not find an association between ACPA positivity and age in men.