TY - JOUR T1 - Menopause and Possible Effect on Association Between Age and Anticyclic Citrullinated Peptide Antibodies in Women At Risk of Rheumatoid Arthritis JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.190836 SP - jrheum.190836 AU - Deshiré Alpizar-Rodriguez AU - Axel Finckh Y1 - 2019/12/01 UR - http://www.jrheum.org/content/early/2019/11/25/jrheum.190836.abstract N2 - We read with interest the article by Berens, et al1 reporting that increasing age was associated with positivity for anticyclic citrullinated peptide antibodies (anti-CCP) 3.1 and anti-CCP–IgA in individuals at risk of rheumatoid arthritis (RA), that is, first-degree relatives (FDR) of patients with RA. We found similar results in a Swiss cohort of FDR: anticitrullinated protein antibodies (ACPA) positivity, particularly anti-CCP3.1, was associated with older age2. However, in contrast to Berens, et al1, we found a peak in prevalence in the age group of 45 to 55 years, particularly among women. ER -