TY - JOUR T1 - Dr. Tselios, <em>et al,</em> reply JF - The Journal of Rheumatology JO - J Rheumatol SP - 1422 LP - 1422 DO - 10.3899/jrheum.190255 VL - 46 IS - 10 AU - KONSTANTINOS TSELIOS AU - DAFNA D. GLADMAN AU - PAULA HARVEY AU - SHADI AKHTARI AU - JIANDONG SU AU - MURRAY B. UROWITZ Y1 - 2019/10/01 UR - http://www.jrheum.org/content/46/10/1422.2.abstract N2 - To the Editor:We thank De Luca and colleagues1 for their interest in our paper2. We agree with the authors that the pathophysiologic mechanisms for abnormal cardiac biomarkers in systemic lupus erythematosus (SLE) are many and may include both inflammatory and ischemic causes among others. We also agree that these conditions may present subclinically. In the paper, we reported that even in the patients who presented with no symptoms at all, further investigations (instigated by the incidental finding of abnormal cardiac biomarkers) revealed myocarditis (n = 1), coronary artery disease (n = 1), uncontrolled systemic hypertension (n = 1), or even pulmonary hypertension (n = 2).Regarding the … Address correspondence to Dr. M.B. Urowitz, University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, 399 Bathurst St., 1E-410B, Toronto, Ontario M5T 2S8, Canada. E-mail: m.urowitz{at}utoronto.ca ER -