RT Journal Article SR Electronic T1 Drs. Mavragani and Moutsopoulos reply JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP jrheum.190837 DO 10.3899/jrheum.190837 A1 Clio P. Mavragani A1 Haralampos M. Moutsopoulos YR 2019 UL http://www.jrheum.org/content/early/2019/09/11/jrheum.190837.abstract AB We were delighted to read the letter by Killian, et al, which challenges the use of the terms primary and secondary human Sjögren syndrome (SS) even in experimental animal models of SS1. These terms were coined almost 40 years ago on the basis of a study that revealed clinical, immunologic, and genetic differences among patients expressing sicca manifestations alone and patients with rheumatoid arthritis (RA) and SS.