PT - JOURNAL ARTICLE AU - Clio P. Mavragani AU - Haralampos M. Moutsopoulos TI - Drs. Mavragani and Moutsopoulos reply AID - 10.3899/jrheum.190837 DP - 2019 Sep 15 TA - The Journal of Rheumatology PG - jrheum.190837 4099 - http://www.jrheum.org/content/early/2019/09/11/jrheum.190837.short 4100 - http://www.jrheum.org/content/early/2019/09/11/jrheum.190837.full AB - We were delighted to read the letter by Killian, et al, which challenges the use of the terms primary and secondary human Sjögren syndrome (SS) even in experimental animal models of SS1. These terms were coined almost 40 years ago on the basis of a study that revealed clinical, immunologic, and genetic differences among patients expressing sicca manifestations alone and patients with rheumatoid arthritis (RA) and SS.