%0 Journal Article %A Mia Glerup %A Peter Stoustrup %A Louise Hauge %A Veronika Rypdal %A Ellen Nordal %A Paula Frid %A Ellen Dalen Arnstad %A Marite Rygg %A Olafur Thorarensen %A Maria Ekelund %A Lillemor Berntson %A Anders Fasth %A Håkan Nilsson %A Suvi Peltoniemi %A Kristiina Aalto %A Sirpa Arte %A Peter Toftedal %A Susan Nielsen %A Sven Kreiborg %A Troels Herlin %A Thomas Klit Pedersen %T Long-term Outcomes of Temporomandibular Joints in Juvenile Idiopathic Arthritis %D 2019 %R 10.3899/jrheum.190231 %J The Journal of Rheumatology %P jrheum.190231 %X Objective To determine the prevalence of orofacial symptoms, dysfunctions, and deformities of the temporomandibular joint (TMJ) in juvenile idiopathic arthritis (JIA) 17 years after disease onset. Methods Drawn from a prospective, population-based Nordic JIA cohort with disease onset from 1997-2000, 420 consecutive cases were eligible for orofacial evaluation of TMJ involvement. The follow-up visit included demographic data, a standardized clinical orofacial examination, and fullface cone-beam computed tomography (CBCT). For comparison, 200 age-matched healthy controls were used. Results Of 420 eligible participants with JIA, 265 (63%) were included (mean age 23.5 ± 4.2 years) and completed a standardized clinical orofacial examination. Of these, 245 had a full-face CBCT performed. At least one orofacial symptom was reported by 33%. Compared to controls, the JIA group significantly more often reported TMJ pain, TMJ morning stiffness, and limitation on chewing. Furthermore, among participants reporting complaints, the number of symptoms was also higher in the JIA. The mean maximal incisal opening was lower in the JIA group (p<0.001), and TMJ pain on palpation was more frequent. Condylar deformities and/or erosions were observed in 61% as assessed by CBCT, showing bilateral changes in about 70%. Risk factors of condylar deformities were orofacial dysfunction or biologic treatment; enthesitis-related arthritis was protective. Conclusion This first study on long-term consequences of TMJ involvement in a population-based JIA cohort reports persistence of comprehensive symptoms, dysfunctions, and damage of the TMJ into adulthood. We suggest interdisciplinary follow-up of JIA patients also in adulthood. %U https://www.jrheum.org/content/jrheum/early/2019/09/11/jrheum.190231.full.pdf