RT Journal Article
SR Electronic
T1 Development and Validation of an OMERACT MRI Whole-Body Score for Inflammation in Peripheral Joints and Entheses in Inflammatory Arthritis (MRI-WIPE)
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1215
OP 1221
DO 10.3899/jrheum.181084
VO 46
IS 9
A1 Simon Krabbe
A1 Iris Eshed
A1 Frédérique Gandjbakhch
A1 Susanne J. Pedersen
A1 Paul Bird
A1 Ashish J. Mathew
A1 Robert G. Lambert
A1 Walter P. Maksymowych
A1 Daniel Glinatsi
A1 Maria S. Stoenoiu
A1 René Poggenborg
A1 Lennart Jans
A1 Jacob L. Jaremko
A1 Nele Herregods
A1 Violaine Foltz
A1 Philip G. Conaghan
A1 Christian E. Althoff
A1 Joel Paschke
A1 Charles Peterfy
A1 Kay-Geert A. Hermann
A1 Mikkel Østergaard
YR 2019
UL http://www.jrheum.org/content/46/9/1215.abstract
AB Objective. To develop a whole-body magnetic resonance imaging (MRI) scoring system for peripheral arthritis and enthesitis.Methods. After consensus on definitions/locations of MRI pathologies, 4 multireader exercises were performed. Eighty-three joints were scored 0–3 separately for synovitis and osteitis, and 33 entheses 0–3 separately for soft tissue inflammation and osteitis.Results. In the last exercise, reliability was moderate-good for musculoskeletal radiologists and rheumatologists with previously demonstrated good scoring proficiency. Median pairwise single-measure/average-measure ICC were 0.67/0.80 for status scores and 0.69/0.82 for change scores; κ ranged 0.35–0.77.Conclusion. Whole-body MRI scoring of peripheral arthritis and enthesitis is reliable, which encourages further testing and refinement in clinical trials.