PT - JOURNAL ARTICLE AU - Anne E. Tebo AU - Robert L. Schmidt AU - Tracy M. Frech TI - Dr. Tebo, <em>et al</em>, reply AID - 10.3899/jrheum.190594 DP - 2019 Aug 01 TA - The Journal of Rheumatology PG - jrheum.190594 4099 - http://www.jrheum.org/content/early/2019/07/23/jrheum.190594.short 4100 - http://www.jrheum.org/content/early/2019/07/23/jrheum.190594.full AB - We read with great interest the response by Drs. Jearn and Kim1 to our letter “Presence of Anti-topoisomerase I Antibody Alone May Not Be Sufficient for the Diagnosis of Systemic Sclerosis”2. We agree with Drs. Jearn and Kim that the antinuclear antibody (ANA)-negative accompanied by antitopoisomerase I antibody (anti-topo I) positivity is not sufficient to diagnose systemic sclerosis (SSc).