PT  - JOURNAL ARTICLE
AU  - Giacomo  de Luca
AU  - Corrado Campochiaro
AU  - Lorenzo Dagna
TI  - Abnormal Cardiac Biomarkers in Patients with Systemic Lupus Erythematosus and No Prior Heart Disease: The Role of Endomyocardial Biopsy
AID  - 10.3899/jrheum.190078
DP  - 2019 Jul 01
TA  - The Journal of Rheumatology
PG  - jrheum.190078
4099  - http://www.jrheum.org/content/early/2019/06/24/jrheum.190078.short
4100  - http://www.jrheum.org/content/early/2019/06/24/jrheum.190078.full
AB  - Tselios, et al reported in their recent study that patients with systemic lupus erythematosus (SLE) who receive prolonged antimalarial (AM) treatment are at increased risk for elevated cardiac biomarkers [brain natriuretic peptide (BNP) and high-sensitivity cardiac troponin I (HS-cTnI)], particularly when persistently elevated creatine phosphokinase (CPK) is present1. Among a well-characterized SLE cohort of 179 patients, the authors found that 16 (all without cardiac disease, renal failure, or pulmonary arterial hypertension) presented an increase of at least 1 cardiac biomarker.