RT Journal Article
SR Electronic
T1 Developing a Preliminary Definition and Domains of Flare in Knee and Hip Osteoarthritis (OA): Consensus Building of the Flare-in-OA OMERACT Group
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP jrheum.181085
DO 10.3899/jrheum.181085
A1 Francis Guillemin
A1 Camille Ricatte
A1 Annica Barcenilla-Wong
A1 Amandine Schoumacker
A1 Marita Cross
A1 Camille Alleyrat
A1 Thomas Buttel
A1 Michel Cembalo
A1 Hakima Manseur
A1 Hema Urban
A1 Bruno Fautrel
A1 Philip G.  Conaghan
A1 Gillian Hawker
A1 Claudia Rutherford
A1 Lyn March
A1 Elisabeth Spitz
A1 David J.  Hunter
YR 2019
UL http://www.jrheum.org/content/early/2019/05/13/jrheum.181085.abstract
AB Flare in knee and hip osteoarthritis (OA) is more than just an exacerbation of pain. Unstructured, semistructured, and focus group interviews followed by Delphi surveys with patients and health professionals (HP) generated candidate domains of an OA flare. Content analysis of interviews with 29 patients and 16 HP extracted 180 statements, which were grouped into 9 clusters. Delphi consensus with 50 patients (Australia, Canada, and France) and 116 HP (17 countries on 4 continents) identified 5 flare domains: pain, swelling, stiffness, psychological aspects, and effect of symptoms. Elements for a preliminary definition of an OA flare are proposed. Registered at clinicaltrials.gov NCT02892058.