PT - JOURNAL ARTICLE AU - Mihaela C. Micu AU - Monika Ostensen AU - Violeta Bojincă AU - Oana Șerban AU - Minodora Mihai AU - Cristina Suța AU - Anamaria Ramazan AU - Luminița Enache AU - Anca Bobircă AU - Sergiu Pătcaș AU - Romeo Micu AU - Ruxandra Ionescu TI - Pregnancy Outcomes in Couples with Males Exposed to Longterm Anti–tumor Necrosis Factor–α Inhibitor Therapies: A Prospective Study AID - 10.3899/jrheum.180588 DP - 2019 Mar 01 TA - The Journal of Rheumatology PG - jrheum.180588 4099 - http://www.jrheum.org/content/early/2019/04/09/jrheum.180588.short 4100 - http://www.jrheum.org/content/early/2019/04/09/jrheum.180588.full AB - Objective To examine the pregnancy achievement and outcomes in couples in which men with spondyloarthritis (SpA) were exposed to tumor necrosis factor inhibitors (TNFi). Methods Information about pregnancies involving fathers with SpA was prospectively collected by 6 Romanian rheumatology centers. Results Twenty-seven patients achieved 33 pregnancies and fathered 30 healthy children. Three elective abortions (personal reasons) and no spontaneous abortions, preeclampsia/eclampsia, stillbirths, congenital malformations, or pathologies in the children were recorded. Five patients showed normospermia before and after longterm TNFi treatment. Conclusion Pregnancy and child outcomes in male patients with SpA exposed to longterm TNFi therapy were reassuring.