PT  - JOURNAL ARTICLE
AU  - Anne E.  Tebo
AU  - Robert L.  Schmidt
AU  - Tracy M.  Frech
TI  - Presence of Antitopoisomerase I Antibody Alone May Not Be Sufficient for the Diagnosis of Systemic Sclerosis
AID  - 10.3899/jrheum.180503
DP  - 2019 Mar 01
TA  - The Journal of Rheumatology
PG  - jrheum.180503
4099  - http://www.jrheum.org/content/early/2019/02/25/jrheum.180503.short
4100  - http://www.jrheum.org/content/early/2019/02/25/jrheum.180503.full
AB  - Systemic sclerosis (SSc) is characterized by altered immune function and vascular damage, which lead to extensive fibrosis. Experts underscore the importance of using SSc-specific autoantibodies to divide the disease into subsets for prognosis, management, and research1,2.