@article {Tebojrheum.180503, author = {Anne E. Tebo and Robert L. Schmidt and Tracy M. Frech}, title = {Presence of Antitopoisomerase I Antibody Alone May Not Be Sufficient for the Diagnosis of Systemic Sclerosis}, elocation-id = {jrheum.180503}, year = {2019}, doi = {10.3899/jrheum.180503}, publisher = {The Journal of Rheumatology}, abstract = {Systemic sclerosis (SSc) is characterized by altered immune function and vascular damage, which lead to extensive fibrosis. Experts underscore the importance of using SSc-specific autoantibodies to divide the disease into subsets for prognosis, management, and research1,2.}, issn = {0315-162X}, URL = {https://www.jrheum.org/content/early/2019/02/25/jrheum.180503}, eprint = {https://www.jrheum.org/content/early/2019/02/25/jrheum.180503.full.pdf}, journal = {The Journal of Rheumatology} }