TY - JOUR T1 - The SPECTRA Collaboration OMERACT Working Group: Criterion Validity of Joint Space Outcomes with High Resolution Peripheral Quantitative Computed Tomography JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.180870 SP - jrheum.180870 AU - Sarah L. Manske AU - Scott C. Brunet AU - Stephanie Finzel AU - Kathryn S. Stok AU - Philip G. Conaghan AU - Steven K. Boyd AU - Cheryl Barnabe Y1 - 2019/01/15 UR - http://www.jrheum.org/content/early/2019/01/11/jrheum.180870.abstract N2 - Objective We assessed construct validity of high-resolution peripheral quantitative computed tomography (HR-pQCT) joint space outcomes by comparison with radiographs in patients with rheumatoid arthritis. Methods In 43 patients, quantitative, volumetric, HR-pQCT measurements were compared with ordinal Sharp/van der Heijde scoring (SvdH) in the 2nd and 3rd metacarpophalangeal joints. Results Generalized estimating equations showed that joint space minimum, SD, and asymmetry by HR-pQCT were associated with SvdH scores (p < 0.05). There was a considerable range in HR-pQCT measurements at SvdH equal to 0. Conclusion HR-pQCT demonstrated construct validity outcomes and provides improved 3-D visualization of joint space. ER -