PT  - JOURNAL ARTICLE
AU  - Priscille Couture
AU  - Pierre-Yves Brillet
AU  - Stéphane Varin
AU  - Benoît Le Goff
AU  - Alain Meyer
AU  - Jean Sibilia
AU  - Stéphane Jouneau
AU  - Dominique Valeyre
AU  - Baptiste Hervier
AU  - Yurdagül Uzunhan
TI  - Sarcoidosis in Patients with Antisynthetase Syndrome: Presentation and Outcome
AID  - 10.3899/jrheum.171098
DP  - 2018 Sep 01
TA  - The Journal of Rheumatology
PG  - 1296--1300
VI  - 45
IP  - 9
4099  - http://www.jrheum.org/content/45/9/1296.short
4100  - http://www.jrheum.org/content/45/9/1296.full
SO  - J Rheumatol2018 Sep 01; 45
AB  - Objective. To investigate the uncommon co-occurrence of antisynthetase syndrome (AS) and sarcoidosis.Methods. From 2000 to 2015, patients with sarcoidosis were extracted from a retrospective multicentric cohort of 352 patients with AS.Results. Ten patients (2.8%; 6 men, 8 whites, 5 smokers, median age 50 yrs) had both AS and sarcoidosis. Most of the time, sarcoidosis and AS occurred simultaneously (n = 7). Antibody testing revealed anti-Jo1 (n = 5), anti-PL12 (n = 4), or anti-PL7 (n = 1). Finally, no patient had a worsening of muscular condition, 5 patients presented respiratory deterioration, 3 remained stable, and 2 showed improvement.Conclusion. Sarcoidosis may be underdiagnosed in patients with AS.