RT Journal Article
SR Electronic
T1 Hospitalization Increases the Risk of Acute Arthritic Flares in Gout: A Population-based Study over 2 Decades
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP jrheum.171320
DO 10.3899/jrheum.171320
A1 Nour Zleik
A1 Mohanad M.  Elfishawi
A1 Zoran Kvrgic
A1 Clement J.  Michet Jr.
A1 Cynthia S.  Crowson
A1 Eric L.  Matteson
A1 Tim Bongartz
YR 2018
UL http://www.jrheum.org/content/early/2018/06/21/jrheum.171320.abstract
AB Objective To assess in-hospital gout flares in patients with gout. Methods Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989–1992 or 2009–2010. Results There were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitalizations. Hospitalization rates increased without reaching statistical significance from 1989–1992 to 2009–2010 [rate ratio (RR) 1.19, 95% CI 0.98–1.45]. The gout flare rate increased significantly during hospitalization (RR 10.2, 95% CI 6.8–14.5). In-hospital gout flare increased the average hospital stay by 1.8 days (p < 0.001). Conclusion Hospitalization increased the risk of gout flares 10-fold. In-hospital gout flares were associated with longer hospitalization.