RT Journal Article
SR Electronic
T1 Short-term Repeat Magnetic Resonance Imaging Scans in Suspected Early Axial Spondyloarthritis Are Clinically Relevant Only in HLA-B27–positive Male Subjects
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 202
OP 205
DO 10.3899/jrheum.170171
VO 45
IS 2
A1 Raj Sengupta
A1 Helena Marzo-Ortega
A1 Dennis McGonagle
A1 Alison Wadeley
A1 Alexander N. Bennett
A1 on behalf of the British Society for Spondyloarthritis
YR 2018
UL http://www.jrheum.org/content/45/2/202.abstract
AB Objective. Our study investigated the natural history of magnetic resonance imaging (MRI)–determined bone marrow edema over a 12-week period in individuals with suspected axial spondyloarthritis.Methods. There were 109 MRI scans performed on 30 patients who fulfilled the Assessment of Spondyloarthritis international Society inflammatory back pain criteria at baseline and at 4, 8, and 12 weeks.Results. There were 29 patients who completed the study. Only 4 (14%) patients changed from MRI-negative to MRI-positive (all HLA-B27–positive, OR 2.74). Three of 7 (43%) male HLA-B27–positive patients, 1 of 8 (12.5%) HLA-B27–positive female patients, and no HLA-B27–negative patients changed from MRI- negative to -positive.Conclusion. Repeat MRI scans within a 12-week period should be considered in HLA-B27–positive males.