RT Journal Article
SR Electronic
T1 Validating Rheumatoid Arthritis Remission Using the Patients’ Perspective: Results from a Special Interest Group at OMERACT 2016
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1889
OP 1893
DO 10.3899/jrheum.161111
VO 44
IS 12
A1 Linda A. Rasch
A1 Maarten Boers
A1 Catherine L. Hill
A1 Marieke Voshaar
A1 Wijnanda Hoogland
A1 Maarten de Wit
A1 Caroline Flurey
A1 Bev Davis
A1 Merete Lund Hetland
A1 Cecilie Heegaard Brahe
A1 Laure Gossec
A1 George A. Wells
A1 Peter Tugwell
A1 Bindee Kuriya
A1 Niti Goel
A1 Jasvinder A. Singh
A1 Cátia Duarte
A1 José Da Silva
A1 Dirkjan van Schaardenburg
A1 Susanna Proudman
A1 Lilian H.D. van Tuyl
YR 2017
UL http://www.jrheum.org/content/44/12/1889.abstract
AB Objective. The Outcome Measures in Rheumatology (OMERACT) working group on the patients’ perspective on remission in rheumatoid arthritis (RA) has been working on this topic since 2010. At OMERACT 2016, progress and preliminary data on validity of measurement instruments for pain, fatigue, and independence in remission in RA were presented, and future directions were explored.Methods. A special interest group was organized, in which the current data on the patients’ perspective on remission were presented. The ongoing study that aimed to validate measurement instruments for pain, fatigue, and independence in a state of low disease activity or remission was presented, and preliminary data on construct validity and discriminative capacity were evaluated cross-sectionally.Results. At OMERACT 2016, the progress of the working group and preliminary data from 142 of the anticipated 300 patients were presented. Selected instruments significantly correlated with the Disease Activity Score in 28 joints (construct validity) and all instruments except 1 discriminated between patients in and patients not in remission. The subsequent discussion mainly focused around 3 points: (1) the formulation of patient perceived remission, (2) the duration of remission, and (3) the measurement of the domain independence. An informal vote indicated a slight preference for working toward modifying the current remission criteria by adding patient-reported outcomes (PRO), or by substituting the patient’s global assessment with 1 or more PRO.Conclusion. More evidence on measuring patients’ perspective on remission in RA is needed before an informed decision can be made regarding development or modification of remission definitions.