PT  - JOURNAL ARTICLE
AU  - Lene Terslev
AU  - Annamaria Iagnocco
AU  - George A.W. Bruyn
AU  - Esperanza Naredo
AU  - Jelena Vojinovic
AU  - Paz Collado
AU  - Nemanja Damjanov
AU  - Andrew Filer
AU  - Georgios Filippou
AU  - Stephanie Finzel
AU  - Frederique Gandjbakhch
AU  - Kei Ikeda
AU  - Helen I. Keen
AU  - Marion C. Kortekaas
AU  - Silvia Magni-Manzoni
AU  - Sarah Ohrndorf
AU  - Carlos Pineda
AU  - Viviana Ravagnani
AU  - Bethan Richards
AU  - Ilfita Sahbudin
AU  - Wolfgang A. Schmidt
AU  - Heidi J. Siddle
AU  - Maria S. Stoenoiu
AU  - Marcin Szkudlarek
AU  - Nikolay Tzaribachev
AU  - Maria-Antonietta D’Agostino
AU  - on behalf of the OMERACT Ultrasound Group
TI  - The OMERACT Ultrasound Group: A Report from the OMERACT 2016 Meeting and Perspectives
AID  - 10.3899/jrheum.161240
DP  - 2017 Nov 01
TA  - The Journal of Rheumatology
PG  - 1740--1743
VI  - 44
IP  - 11
4099  - http://www.jrheum.org/content/44/11/1740.short
4100  - http://www.jrheum.org/content/44/11/1740.full
SO  - J Rheumatol2017 Nov 01; 44
AB  - Objective. To provide an update from the Outcome Measures in Rheumatology (OMERACT) Ultrasound Working Group on the progress for defining ultrasound (US) minimal disease activity threshold at joint level in rheumatoid arthritis (RA) and for standardization of US application in juvenile idiopathic arthritis (JIA).Methods. For minimal disease activity, healthy controls (HC) and patients with early arthritis (EA) who were naive to disease-modifying antirheumatic drugs were recruited from 2 centers. US was performed of the hands and feet, and scored semiquantitatively (0–3) for synovial hypertrophy (SH) and power Doppler (PD). Synovial effusion (SE) was scored a binary variable. For JIA, a Delphi approach and subsequent validation in static images and patient-based exercises were used to developed preliminary definitions for synovitis and a scoring system.Results. For minimal disease activity, 7% HC had at least 1 joint abnormality versus 30% in the EA group. In HC, the findings of SH and PD were predominantly grade 1 whereas all grades were seen in the EA cohort, but SE was rare. In JIA, synovitis can be diagnosed based on B-mode findings alone because of the presence of physiological vascularization. A semiquantitative scoring system (0–3) for synovitis for both B-mode and Doppler were developed in which the cutoff between Doppler grade 2 and grade 3 was 30%.Conclusion. The first step has been taken to define the threshold for minimal disease activity in RA by US and to define and develop a scoring system for synovitis in JIA. Further steps are planned for the continuous validation of US in these areas.