RT Journal Article SR Electronic T1 Basic and Translational Science: A Report from the GRAPPA 2016 Annual Meeting JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 679 OP 683 DO 10.3899/jrheum.170143 VO 44 IS 5 A1 James G. Krueger A1 Bruce Kirkham A1 Christopher T. Ritchlin YR 2017 UL http://www.jrheum.org/content/44/5/679.abstract AB Rapid advances in effective treatments for psoriasis and psoriatic arthritis (PsA) have emerged from improved understanding of cell subsets and critical mediators that promote tissue inflammation and destruction. More specifically, increased knowledge of innate immunity and the important involvement of cytokines in the interleukin (IL)-23–IL-17 axis as key mediators of psoriatic plaque and joint inflammation in both psoriasis and PsA have led to new theories of immunopathogenesis. Herein we summarize recent discussions on IL-17–related pathways and their relationship to psoriasis and PsA.