TY - JOUR T1 - Predictors of Relapse after Discontinuing Systemic Treatment in Childhood Autoimmune Chronic Uveitis JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.161336 SP - jrheum.161336 AU - Gabriele Simonini AU - Claudia Bracaglia AU - Marco Cattalini AU - Andrea Taddio AU - Alice Brambilla AU - Cinzia De Libero AU - Denise Pires Marafon AU - Roberto Caputo AU - Rolando Cimaz Y1 - 2017/04/01 UR - http://www.jrheum.org/content/early/2017/03/28/jrheum.161336.abstract N2 - Objective To identify clinical predictors of relapse in childhood autoimmune chronic uveitis after stopping systemic treatment. Methods A retrospective, multicenter, cohort study. Results Ninety-four children in remission, receiving no treatments and with at least a 6-month followup, were enrolled. A higher probability of maintaining remission after discontinuing treatment was shown in idiopathic compared with juvenile idiopathic arthritis uveitis (Mantel-Cox chi-square = 23.21) if inactivity had been obtained within 6 months from starting systemic treatment (Mantel- Cox chi-square = 24.17) and by antitumor necrosis factor-α treatment (Mantel-Cox chi-square = 6.43). Conclusion Type of disease, time, and type of systemic therapy to achieve inactivity predict different duration of uveitis remission after treatment withdrawal. ER -