%0 Journal Article %A ALBERTO CAULI %A ALESSANDRO MATHIEU %T Th17 and Interleukin 23 in the Pathogenesis of Psoriatic Arthritis and Spondyloarthritis %D 2012 %R 10.3899/jrheum.120234 %J The Journal of Rheumatology %P 15-18 %V 89 %X Psoriatic arthritis and spondyloarthritis (SpA) are complex immune-mediated diseases affecting peripheral and axial joints. T cells have been considered fundamental in triggering the disease and maintaining the process in the chronic phase. The recent discovery of the CD4+ Th17 lymphocyte subset and the interleukin 23/interleukin 17 axis has further contributed to the definition of unknown pathways, challenging previous models and the role of Th1/Th2 T cells in immune mediated diseases, including SpA. %U https://www.jrheum.org/content/jrheumsupp/89/15.full.pdf